Between a sentence and a list or explanation:
They have only one
option left now: turn themselves in and
apologize.
Quotations with independent clauses:
My German
Professor had this to say about grammar:
"Spoken language came first. Grammar is just an attempt to explain the
mess after the fact."
*Notice the difference between this sentence and the one above:
My German Professor said, "Spoken language came
first. Grammar is just an attempt to explain the mess after the fact."